You can use CloudLinux Selector to enable ionCube Loader in cPanel.
1. Log in to your cPanel account.
2. In the Software section, click on Select PHP Version.
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3.Under the Account Global Settings, go to the Extensionstab.

Note: If it shows an error related to the Native PHP version, change to a non-Native PHP version first.
4. Checkmark the ioncube_loader. Once enabled, it will display a success message.

The message will read that the module ionCube Loader is saved.

You have successfully enabled ionCube Loader using the CloudLinux Selector in cPanel.
Note: This tutorial covers enabling Ioncube Loader on all domains. To enable it for an individual domain, go to Per Domain Settings, click on the Per Domain option, and then select ioncube_loader for the domain you wish to enable it on.